Saturday, July 24, 2021

Vicodin: How To Know Overdose?

The standard therapeutic range for hydrocodone is 5-60 mg/day and you can order Vicodin online. In people with a high susceptibility to opioids, even this amount can cause typical symptoms of intoxication. An overdose is suspected with a sharp aggravation of side effects and the appearance of the following signs:

  • pale bluish skin coloration
  • disturbances of consciousness from stupor to complete absence
  • inability to focus gaze, double vision, nystagmus (frequent involuntary eye movements)
  • severe pain in the region of the heart
  • decrease in body temperature
  • cold clammy sweat
  • gait disturbance
  • a characteristic feature is an unnaturally sharp narrowing of the pupils to the size of a pinhead
  • difficulty breathing
  • drop in blood pressure
  • acute urinary retention
  • cramping abdominal pain
  • threadlike pulse
  • cardiac arrest

The likelihood of an overdose increases multiple times when mixing hydrocodone with alcoholic beverages, amphetamines, and barbiturates. Sometimes the poisoning is accompanied by convulsions. Death occurs from paralysis of the respiratory center.

Popular among Americans, Vicodin contains only paracetamol in addition to hydrocodone. Taking a large dose of analgesic, a person aggravates the severity of the condition due to acetaminophen poisoning. Therefore, signs of severe renal-hepatic failure (encephalopathy, jaundice, coma, generalized edema) can be added to the symptoms of intoxication.

Recreational Use

Regular use of opioids is fraught, first of all, with the formation of severe dependence. Tolerance also develops rapidly, so the active dose in people with addiction is much higher than the therapeutic dose. The outcome of abuse is wasting cognitive deficit and multiple organ failure.

The recreational dose depends on the characteristics of the organism. For a beginner, the standard amount prescribed in the medical instructions for the drug will suffice. Experienced users take large doses, often in combination with other psychoactive substances. The rapid addition of withdrawal symptoms (“withdrawal”) speaks of physical dependence on the drug.

The pathological addiction is characterized by a progressive course, that is, it is aggravated in accordance with the duration of the use of the opioid analgesic. Malignant forms of drug addiction are characteristic of emotionally unstable people with a burdened history – the presence of mental disorders, alcohol, and other substance abuse.

Anesthesia in adolescents leads to a lag in psychophysical development, antisocial behavior. Cases of premature, including violent, death is not uncommon. Hydrocodone, in addition to the well-known Doctor House.

The appearance of drug addicts is characteristic, especially with a long period of abuse. They look much older than their age, the skin is pale with a yellowish tinge, brittle hair, and nails. A critical decrease in body mass, up to and including exhaustion, is often found.

Toxicology

The neutralization of the substance occurs in the liver. As a result, active metabolites are formed, which can be quickly detected in almost all body fluids. Blood and urine are the preferred choices for forensic investigations.

The problem is that screening tests (urine strips) often give false-positive results. Analyzers cross-react to the presence of other opiates. The concentration of hydrocodone in the blood plasma when taking therapeutic doses is 5-30 mcg / l, in drug addicts – more than 100-200 mcg / l.

Conclusions

Hydrocodone is recognized as a drug. The substance has a high potential for the formation of addiction, quickly leading to severe health consequences. In the outcome of the disease, changes in the psyche can be observed – patients are disabled, cognitive-intellectual activity is reduced, memory disorders are characteristic.

All patients with isolated drug dependence are subject to combination treatment. The main goal of Vicodin for sale is to eliminate the pathological addiction with a replacement for a safe analgesic if the situation requires it. The prognosis for combined forms of drug addiction is often unfavorable.

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